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Prophylaxis

Articles:

 

Should oral fatty acid supplements be used in the prevention of SARS-COV-2 infection or as treatment of COVID-19?

  • Key Finding: There is lack of clinical evidence supporting the role of oral fatty acid supplements as prevention of SARS-CoV-2 infection and adjunctive therapy for patients with COVID-19

 

Should zinc supplements be used in the prevention of COVID-19?

  • Key Finding: Currently, there is no clinical evidence that zinc supplements should be used to prevent COVID-19

 

Should Bacillus Calmette–Guérin (BCG) vaccine be used in the prophylaxis of COVID-19?

  • Key Finding: At present, there is no sufficient evidence to support the use of BCG vaccine as prophylaxis for COVID-19.

 

Should chloroquine or hydroxychloroquine be used in the prophylaxis of COVID-19?

  • Key Finding: There is currently NO EVIDENCE to support chemoprophylaxis using chloroquine or hydroxychloroquine against COVID-19.

 

Should Melatonin be used as prophylaxis for COVID-19?

  • Key Finding: Currently, there is no sufficient evidence to support the use of melatonin as prophylaxis for COVID-19 as there were no published clinical trials nor on-going trials found.

 

Updated as of June 9, 2020

 


Through the volunteer work of more than 50 EBM practitioners, methodologists and students from the UP Institute of Clinical Epidemiology and Asia-Pacific Center for Evidence-Based HealthCare, the Philippine Society of Microbiological and Infectious Diseases (PSMID) had graciously agreed to host these rapid evidence reviews on COVID19. The aim is to retrieve, appraise, summarize and update the available evidence on COVID-related management, to assist the frontline health workers, local policymakers and government officials in their evidence-based critical decision-making.
 
The reviews should not replace individual clinical judgement and the sources cited should be checked. The views are not a substitute for professional medical advice. The views expressed represent the views of the authors and not necessarily those of their host institutions. This may change as new evidences emerges.
 
A discussion of the general methods used can be found here: Rapid Evidence Review General Methods.
 
For any questions or information, please email [email protected].

 

 

 

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